Bosses
Bosses are large and challenging enemies linked to the various biomes. Their spawns are located at set distances from The Core at randomised angles. Defeated bosses drop useful items and some gate game progression.
Early game[edit]
| Health | Biome | Distance |
| 2,459 | Dirt | 65 |
Glurch is one of the three Bosses of early game. It is usually the first boss a player encounters, always 65 tiles from the core. Glurch has an underground shaking jump attack similar to that of the regular sized Orange and Red Slime mobs found close by. Also modestly challenging to fight.
When defeated, the 
Bearded Merchant NPC is released. Glurch always drops 
Glurch Eye, one of the three items required to power up The Core. Once emplaced in its Boss Statue, the world save file is marked with this item icon.
| Health | Biome | Distance |
| 8,061 | Clay/Stone | 200 (encircling) |
Ghorm is one of the three bosses in early game. When defeated, Ghorm will drop 
Ghorm's Horn, one of the three items required to power up the core. Your world save file will also be marked with the same icon.
Ghorm spawns halfway between the Core and the Great Wall. It circles around the Core, moving between The Clay Caves and The Forgotten Ruins, destroying everything in its path. 
Ghorm the Devourer Scanner can be used to locate its position on the map, though largely unnecessary, as you can always find its track no matter which direction you go. Ghorm track appears approximately 220 tiles away from the core. You can use this measurement against any other bosses for reference. The track is approximately 8 tiles wide, filled with ground slimes.
To respawn Ghorm after it has been killed, place 
Ghorm Summoning Idol on its rune circle. The idol can be purchased from the 
Cloaked Merchant. The merchant will restock their items after some time has passed.
| Health | Biome | Distance |
| 14,513 | Stone | 300 |
Malugaz is one of the three bosses in early game. When defeated, Malugaz will drop 
Stolen Crystal Heart, one of the three items required to power up the core. Your world save file will also be marked with the same icon.
Malugaz' arena is located in The Forgotten Ruins. 
Malugaz the Corrupted Scanner can be used to locate its position on the map. It spawns approximately 350 tiles away from the core at a random angle, or 1.59 times longer radius than Ghorm's track.
To spawn or respawn Malugaz, place 
Skull of the Corrupted Shaman on the sigil at the center of the throne room. The skull can be crafted by using 
3Crystal Skull Shard. Once you have three of them, use the item to craft it. Skull shards are dropped randomly from caveling enemies in the forgotten ruins.
Mid game[edit]
| Health | Biome | Distance |
| 31,813 | Nature | 550 |
Azeos is one of the three titans in the game. When defeated, Azeos will drop 
Soul of Azeos, one of the three souls required to advance the story. Your character save file will also be marked with the same icon.
Azeos' arena is located in the Azeos' Wilderness. 
Azeos the Sky Titan Scanner can be used to locate its position on the map. It spawns approximately 600 tiles away from the core at a random angle, or 1.27 times longer radius than the great wall. The arena is fully lit, and there are many bird droppings and feathers on the ground. A giant bird shadow can be seen passing by occasionally.
To spawn or respawn Azeos, place 
Large Shiny Glimmering Object anywhere in the arena. You might have to wait up to 5 minutes or higher for its shadow to reappear before you can respawn it. The object can be crafted by talking to the Spirit Merchant that appears when placing Ancient Hologram Pod on the ground.
| Health | Biome | Distance |
| 90,772 | Sea | 650 |
Omoroth is one of the three titans in the game. When defeated, Omoroth will drop 
Soul of Omoroth, one of the three souls required to advance the story. Your character save file will also be marked with the same icon.
Omoroth's arena is located in the The Sunken Sea. 
Omoroth the Sea Titan Scanner can be used to locate its position on the map. It spawns approximately 1100 tiles away from the core at a random angle, or 2.34 times longer radius than the great wall. The arena is fully lit, and there are 5 giant whirlpools.
To spawn or respawn Omoroth, equip 
Expert Lure in your off-hand, and use a fishing rod. Aim your lure on one of the whirlpools, wait until it bites, and then pull it out. You might have to wait up to 5 minutes or higher for its soul to disappear before you can respawn it. The lure can be crafted by talking to the Spirit Merchant that appears when placing Ancient Hologram Pod on the ground.
| Health | Biome | Distance |
| 160,799 | Desert | 600 |
Ra-Akar is one of the three titans in the game. When defeated, Ra-Akar will drop 
Soul of Ra-Akar, one of the three souls required to advance the story. Your character save file will also be marked with the same icon.
Ra-Akar's arena is located in the The Desert of Beginnings. 
Ra-Akar the Sand Titan Scanner can be used to locate its position on the map. It spawns approximately 1000 tiles away from the core at a random angle, or 2.15 times longer radius than the great wall.
To spawn or respawn Ra-Akar, place 
Thumper on the arena. It can be crafted by talking to the Spirit Merchant that appears when placing Ancient Hologram Pod on the ground.
Late game[edit]
Optional[edit]
| Health | Biome | Distance |
| 24,671 | Hive | 330 |
The Hive Mother is an optional early game side boss that is not required to be defeated to advance the story.
The Hive Mother spawns in the Larva Hive Biome. 
Hive Mother Scanner can be used to locate its position on the map. It spawns approximately 330 tiles away from the core at a random angle, or 1.5 times longer radius than Ghorm's track.
To respawn the Hive Mother after it has been killed, place 
Hive Mother Summoning Idol on its rune circle. The idol can be purchased from the Cloaked Merchant. The merchant will restock their items after some time has passed.
| Health | Biome | Distance |
| 39,155 | Nature | 600 |
Ivy is an optional side boss that is not required to be defeated to advance the story.
It spawns in the Azeos' Wilderness, approximately 900 tiles away from the core at a random angle, or 1.91 times longer radius than the great wall. 
Ivy the Poisonous Mass Scanner can be used to locate its position on the map. When you get close, your screen will shake periodically. Its lair is a big open space covered with ground poison slimes. These ground slimes slows your movement speed and poisons you, reducing your healing received by 75%.
To respawn Ivy after it has been killed, place 
Giant Slime Summoning Idol on its rune circle. The idol can be purchased from the Cloaked Merchant. The merchant will restock their items after some time has passed.
| Health | Biome | Distance |
| 84,551 | Sea | 700 |
Morpha is an optional side boss that is not required to be defeated to advance the story.
It spawns in The Sunken Sea, approximately 1400 tiles away from the core at a random angle, or 2.97 times longer radius than the great wall. 
Morpha the Aquatic Mass Scanner can be used to locate its position on the map. When you get close, your screen will shake periodically. Its lair is a big open space covered with ground slippery slimes. These ground slimes turn your movement slippery, making your character harder to control.
To respawn Morpha after it has been killed, place Giant Slime Summoning Idol on its rune circle. The idol can be purchased from the Cloaked Merchant. The merchant will restock their items after some time has passed.
| Health | Biome | Distance |
| 160,799 | Lava | 650 |
Igneous is an optional side boss that is not required to be defeated to advance the story.
It spawns in Molten Quarry, approximately 1400 tiles away from the core at a random angle, or 2.97 times longer radius than the great wall. 
Igneous the Molten Mass Scanner can be used to locate its position on the map. When you get close, your screen will shake periodically. Its lair is a big open space covered with ground lava slimes. These ground slimes burn your character, dealing constant damage.
To respawn Igneous after it has been killed, place Giant Slime Summoning Idol on its rune circle. The idol can be purchased from the Cloaked Merchant. The merchant will restock their items after some time has passed.
| Health | Biome | Distance |
| 24,188 | Varies | Varies |
King Slime is an optional Boss not necessary for game progression. He can be spawned by players using a 
Crown Summoning Idol at any of the slime boss runes around a world. Although his stats currently place him around mid-game in difficulty.
King Slime exhibits the same behaviour as the other giant slime bosses, attempting to jump onto players. In addition he sheds short live regular sized Royal Slime mobs when taking damage. He is the Core Keeper side of a crossover with Terraria, in which he also appears.
| Health | Biome | Distance |
| 9,641/segment | Sea | Varies (roaming) |
Atlantean Worm is an optional Boss not necessary for game progression. It can be seen roaming the Sunken Sea at around 800-1000 tiles away from the Core. 
Atlantean Worm Scanner can be used to locate its position on the map. Players may fight the boss by placing a 
Bait Pillar close to it.
Event[edit]
| Health | Biome | Distance |
| 24,671 | Hive | 330 |
Haunted Hive Mother is a seasonal Halloween form of the Hive Mother.
Haunted Hive Mother uses the same arena as the Hive Mother which is located in the Larva Hive Biome. Hive Mother Scanner can be used to locate its position on the map. It spawns approximately 330 tiles away from the core at a random angle, or 1.5 times longer radius than Ghorm's track.
To spawn or respawn Haunted Hive Mother, place 
Haunted Hive Mother Summoning Idol on its rune circle. The idol can be obtained randomly when opening a 
Samhain Goodie Bag dropped from Big Larva, Caveling, Caveling Shaman, and Caveling Brute while Creepy Costume Party is running.
| Health | Biome | Distance |
| 31,813 | Nature | 550 |
Awakened Azeos is a seasonal Easter form of Azeos the Sky Titan.
Azeos' arena is located in the Azeos' Wilderness. Azeos the Sky Titan Scanner can be used to locate its position on the map. It spawns approximately 600 tiles away from the core at a random angle, or 1.27 times longer radius than the great wall. The arena is fully lit, and there are many bird droppings and feathers on the ground. A giant bird shadow can be seen passing by occasionally.
To spawn or respawn Awakened Azeos, place 
Large Golden Egg anywhere in the arena. You might have to wait up to 5 minutes or higher for its shadow to reappear before you can respawn it. Large Golden Egg can be crafted from Easter eggs obtained during The Great Egg Hunt.